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These inherent constraints preclude causal inference between GLP-1 RAs and NAEs while preventing incidence rate calculations 75

While these medications have shown promising results in helping patients control blood sugar and shed excess weight, there is an emerging concern about their potential impact on eye health

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In this scenario, greater degradation of GLP-1 (and the other incretin, GIP), with a consequent impairment of the incretin effect would contribute to worsening of glycaemic control

Potential modulation of central pain processing through GABAergic effects