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Reducing calorie intake while eating nutrient-dense foods leads to faster progress

The SCALE program also included two RCT conducted in patients with T2D on background oral anti-diabetes medications with 21,22 /without 22 insulin, aiming to assess the efficacy of liraglutide 3.0 mg on weight loss at 56 weeks

Yes, it does

Methods Under registration number CRD42024613545, the research protocol for this study was submitted to the International Prospective Register of Systematic Reviews (PROSPERO)

However, not all models respond similarly and a recent study suggests that there may be sex differences that need to be further addressed [18]