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Pain 136 , 202210 (2008)

GLP-1RAs disrupt this inflammatory cascade by diminishing adipose tissue macrophage infiltration, enhancing insulin sensitivity via reduced inflammatory signaling, and safeguarding pancreatic -cells from inflammatory harm (Pang et al

Whether this mechanism translates into greater weight loss than dual-agonist therapies remains a hypothesis no head-to-head clinical trials have yet been conducted

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