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So, I have no doubt GLP1 agonists will work as adjunctive therapy, but why are we skipping dietary studies to better understand the effects of insulin resistance on immune dysfunction and the benefits of ketosis on optimal immune function

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Our goal with our Rejuva platform is to develop gene therapy candidates that can durably change the trajectory of both obesity and T2D, and todays results further consolidate preclinical proof-of-concept data for the viability of this approach. Fractyl Health anticipates progressing its GLP-1 PGTx through lead optimization and IND-enabling toxicity studies in 2024.

Once the mitochondrial membranes are protected and repaired, the electron transport chain can resume functioning efficiently without leaking excessive free radicals

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