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Melanotan II is structurally and pharmacologically distinct from both the more MC1R-skewed -MSH analog approved for erythropoietic protoporphyria and the MC4R-leaning linear cleavage analog approved for a premenopausal hypoactive disorder neither of which is this compound, and neither of which shares the same CAS registry number, molecular formula, or clinical development history

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Women with polycystic ovary syndrome (PCOS) and obesity often have elevated androgen levels, including testosterone, contributing to symptoms such as hirsutism, acne, and irregular menstruation

Off-label use is carried out solely at the doctor's clinical discretion and responsibility, with the patient's fully informed consent

Alcohol consumption can also significantly decrease sperm quality, as displayed by the figure below