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Semaglutide demonstrated average weight loss of 10-15% of body weight over 68 weeks in clinical trials, with some patients achieving weight reduction exceeding 20% in longer-term studies

It is necessary to thoroughly understand the basis of metal-based NP toxicity before extensive metal-based NPs can be safely applied to human beings

Retatrutide is currently considered one of the most advanced metabolic weight loss therapies being studied because it targets GLP-1, GIP, and glucagon receptors together

Others want clarity on whether these medications are safe for long-term use