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Theres a lot to be learned about the oral versions, Dushay said

A successful injection typically feels like brief pressure or a quick pinchnot sharp or prolonged pain

They can advise you on the right dosage schedule, address GLP-1 nausea or any other side effects that come up, and help you stay motivated during titration

In a typical healthy weight loss scenario, about 75 percent of weight loss comes from fat, while roughly 25 percent comes from fat-free mass, including muscle, says Sriram Machineni, MD, an endocrinology, diabetes, and metabolism expert at Montefiore Health Systems in New York City

She emphasizes listening to the patient, treating systemic contributors, and combining targeted tools with foundational lifestyle work