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As a result, pain may return more quickly, require higher doses, or spread beyond the original sitedriving a cycle of escalating medication use without meaningful resolution (27,31)

The lack of central carbon and nitrogen catabolism not only leads to energy deficiency but also reduces the supply of the main metabolite anabolic precursors such as pyruvate, acetyl-CoA, glucose-6-phosphate, and erythrose 4-phosphate used for biomass biosynthesis 21

Vas de administracin : Subcutnea: va estndar

Monitor hydration and electrolytes, especially if experiencing gastrointestinal side effects

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