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The results showed that Exendin-4 also promoted bone marrow-derived macrophage polarization to M2 phenotye and TGF-1 secretion via PKA-STAT3 signaling (31)

Therefore, we conclude our crystal structure represents a physiologically relevant snapshot of GLP-1R in an inactive peptide-free state

GLP-1 microdosing allows these patients to access the metabolic benefits while minimizing gastrointestinal discomfort, fatigue, or other adverse reactions

GLP-1 improves the neuronal supportive ability of astrocytes in Alzheimers disease by regulating mitochondrial dysfunction via the cAMP/PKA pathway