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Crosstalk between macrophages, T cells, and iron metabolism in tumor microenvironment

Kise S, Morita S, Sakaki T, Kimura H, Kinuya S, Yasuda K

Accumulation of iron produces specific phospholipid hydroperoxides, which are counteracted endogenously by cells through the system xc - /GSH/GPX4 axis

Indeed, AOXs are extensively consumed due to their easy availability through different retail outlets ( In this review, we comprehensively discussed the types, mechanisms of action and safety profile of AOXs that are commonly prescribed in infertility clinics

Flooding the system doesnt necessarily translate to better outcomes