GLP-1 and GIP receptor signaling in beta cells - A review of receptor interactions and co-stimulation
semaglutide The SURPASS-2 clinical trial compared tirzeparide to semaglutide head to head
Practical Application Polyphenol-rich foods: Pomegranates, cranberries, blueberries, green tea Prebiotic fibers: Garlic, onions, leeks, asparagus Omega-3 sources: Fatty fish, walnuts, flaxseeds, chia seeds Fermented foods: Yogurt, kefir, sauerkraut, kimchi Avoid excessive antibiotics: When possible, preserve gut bacteria diversity Limit artificial sweeteners: May negatively impact beneficial bacteria Regular exercise: Supports beneficial bacterial populations Adequate sleep: 7-9 hours supports microbiome balance Strategy 4: Fatty Acid Signaling for L-Cell Activation The Science: L-cells express receptors that detect specific fatty acids in the intestinal lumen
It is estimated that as many as half of diabetics have underlying NAFLD, with a higher risk of progression to NASH with fibrosis than non-diabetics
The program provides a year of free Noom or substantial medication discounts to anyone who regains the weight within 18 months following a 12-month course of Noom GLP-1 Rx , including Nooms taper protocol