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In 2013, an article was published claiming the hypothesis that TMAO is a causative compound of atherosclerosis. The hypothesis intrigued many researchers because it pointed out the relationship between intestinal microbiota and atherosclerosis

Severe or prolonged gastrointestinal symptoms can lead to dehydration and acute kidney injury in some cases, so maintaining adequate fluid intake is important

Research has also examined anti-inflammatory effects, which may explain why copper peptide products - particularly serums, which allow for effective absorption - are often well-tolerated even by those with reactive skin

Environ Microbiol 12:304314

doi: 10.3389/fphar.2025.1526623 9 TangSAZhangCOoWMFuKRisbergMABierma-ZeinstraSMet al