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Glutathione and glutamate were significantly correlated with each other in all three brain regions

Glutathione deficiency can lead to numerous health problems and worsen oxidative damage, perpetuating the cycle of chronic inflammation

Even so, in healthy adults, even with strict vegetarian patterns, a clinical deficiency is uncommon because endogenous synthesis usually meets needs, although context (age, nutritional status, illness) can modify this situation

145,146 Knocking down PARP1 can extend the longevity of Drosophila by regulating PARylation and AMPK activity

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