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It is a targeted, three-organism system

There is a significant negative correlation between telomere length and the aging rate in different species, with some long-lived species having longer telomere lengths and short-lived species having shorter telomere lengths

While PGRPs are responsible for mediating Toll activation, Gram-negative binding protein GNBP1 and GNBP3 were reported to be responsible for Gram-positive bacterial infections and fungal infections respectively (127)