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Ali MM, Alauddin M, Mahmud I, Joon A, Momin AB, Cortez JR, Chen H, Tan L, Chan W, Anantha RW, Stolley DL, Shamsutdinova D, Evans K, Merric-Bernstam F, Herlyn M, Thomas M, Chen Y, Davies MA , Chattopadhyay C

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The first dose is usually 1000 mcg (1 mg)

Consistent with the mean of 10% weight loss observed in the naltrexone-bupropion group, which was maintained through 12 months, we observed modest improvements in the obesity-related parameters in several domains relevant to cardiometabolic risks: glycaemic control (HbA1c), lipid metabolism (LDL-C levels), liver parameters (ALT and AST levels, CAP and LS on VCTE)

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