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Notably, this heat stroke-induced LIRI differs fundamentally from reperfusion injury in hypovolemic shock or surgical contexts: in heat stroke, reperfusion is preceded by hyperthermia-induced endothelial damage and systemic inflammatory priming, which amplify oxidative stress (e.g., xanthine oxidase activation) and neutrophil infiltration

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Considered by some to be the master antioxidant, glutathione plays a crucial role in shielding cells from oxidative stress

Their provider notes the improvement but points out that their alcohol intake of four to five drinks per week is likely limiting further improvement

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