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This leads to the recruitment of neutrophils and the release of cytokines, increasing the inflammatory response

Kim DH, Kim SW, Kim SW, Kang JM

Additionally, Ca 2+ overload induces K + efflux through Gardos channels [187] and promotes activation of cytoskeleton-degrading calpain [188], which consequently leads to the cell shrinkage and membrane blebbing, respectively

To measure the early IgM response, the same dose of TNP-Ficoll (Biosearch Technologies F-1300-100) was administered i.p., and blood was collected one day previous injection and 3, 5, and 7 days post injection

Skipping intake means the clinic is not screening for contraindications (pregnancy, autoimmune flare, anticoagulant use, recent dental work, prior filler complications)