Where enhanced activity is observed, translational studies need to establish that enhanced activity is not counterproductive in terms of just increasing drug potency and its associated side effects, and hence no antitumour benefit
Name, J
doi:10.1111/jocd.13350 Oben, J
Glutathione binds to and neutralizes oxidative compounds such as carbon radicals, hydroperoxides, superoxide, nitric oxide, peroxynitrites, and lipid peroxides.* [3] Mitochondria are the energy-producers of each cell and depend on glutathione for protection.* When free radicals damage mitochondria, their activity becomes sluggish, and they can contribute to further mitochondrial oxidation
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