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The gastrointestinal side effects of GLP-1 agentsparticularly vomiting and diarrheacan lead to depletion of essential electrolytes including sodium, magnesium, potassium, and calcium, all of which are critical for normal muscle contraction and relaxation

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Side Effect Management: Injectable : If you have a bad reaction to the shot, the side effects may linger for the full week as the drug slowly releases

What Your Clinician May Check diabetes medications that may increase low blood sugar risk when appetite drops blood pressure medications that may need adjustment as weight changes medications that irritate the stomach, because nausea risk may rise supplements or over-the-counter products that affect digestion Also, semaglutide eligibility and screening should include a practical plan for side effects