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The Rationale for Dual Targeting The concept of dual GIP/GLP-1 receptor agonism emerged from observations that patients with type 2 diabetes often exhibit reduced GIP sensitivity, while GLP-1 responses may remain relatively preserved

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Metabolic studies exploring the relationship of dietary sulfur intake to urinary excretion of inorganic sulfate The lack of available data on the relationship of dietary supplements, such as chondroitin sulfate and its analogues, to dietary intake of sulfur and to any possible relationship encouraged us to contemplate a series of human metabolic/balance studies that would relate intake of proteins, dietary supplements containing sulfur and SAA to sulfate excretion

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