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We report that in obese mice, GLP-1 medicines predominantly reduce body fat alongside a small but significant decrease in LBM

After 16 weeks of liraglutide therapy, the patient achieved a 9.7 kg weight reduction, demonstrating that GLP-1 RAs can re-induce weight loss even after prior surgical failure [68]

Good data are important as large numbers of people are taking these drugs outside medical supervision and there is wide potential for misuse

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These results indicated that LT triggered ferroptosis in PCa cells by enhanced TFEB nuclear translocation and boosting ferritinophagy (93)