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In one study, people taking tesamorelin lost about 0.9 pounds, while those on placebo had no change in body weight

Total cholesterol came down nearly 20 points, bad cholesterol came down 15 points, fasting sugar went down, blood pressure got better, so, you know, semaglutide and other of these GLP-1 agonists even recently received its FDA indication to reduce the risk for heart disease

Economic evaluation of weight loss and transplantation strategies for kidney transplant candidates with obesity

Cheng AY, Fantus IG: Oral antihyperglycemic therapy for type 2 diabetes mellitus

Initiating at a lower dose and titrating up helps to minimize these side effects