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This multi-receptor profile is structurally and pharmacologically distinct from single-agonist (GLP-1R only, e.g

PubMed pubmed.ncbi.nlm.nih.gov [54] Semaglutide for the treatment of obesity PubMed pubmed.ncbi.nlm.nih.gov [55] Value of GLP-1 receptor agonists versus long-acting insulins for type 2 diabetes patients with and without established cardiovascular or chronic kidney diseases: A model-based cost-effectiveness analysis using real-world data ScienceDirect science/article/abs/pii/S0168822723001006

doi:10.3390/brainsci7020020

Sandy Bassin, MD Medical Reviewer Sandy Bassin, MD, is an endocrinology fellow at Mount Sinai in New York City