Monica Vermani, a clinical psychologist and author of A Deeper Wellness: Conquering Stress, Mood, Anxiety, and Traumas , says seven out of the nine clients she sees who take semaglutide have experienced positive effects from it, including faster progress in weight loss due to reduced cravingsand an inability to binge eat. The other two patients continued their unhealthy eating habits, but in terms of their mental health, she says none of the nine reported a loss of enthusiasm, joy or lust for life. Instead, she says, Most of them were very happy with their weight loss, after years of unsuccessful yo-yo dieting. Perhaps the best-case scenario for anyone whos taking semaglutide is to one day be able to stop taking it and maintain a trim physique, which is not out of the realm of possibility for many who are on it
As a GLP-1 (glucagon-like peptide-1) receptor agonist, it mimics a natural hormone in your body that plays a crucial role in regulating appetite and blood sugar
You are pharmacologically stimulating melanocytes, or the pigment producing cells in the skin, which raises safety questions, she says
An assay that lacks sensitivity at low cell numbers or introduces variability between plates, will undermine every downstream result
Philis-Tsimikas A, Bajaj HS, Begtrup K, et al