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The Gs heterotrimer engages with the receptor through the same interface observed in peptide-agonist structures, with the alpha-5 helix of Gs-alpha inserting into the intracellular cavity and making contacts with TM3, TM5, TM6, and intracellular loop 2 (ICL2)

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Sam earned his bachelors degree in philosophy from Stanford University and his doctorate (Ph.D.) in neuroscience from the University of California, Los Angeles (UCLA)

(2020) Acta Crystallogr D Struct Biol 76 : 1222-1232 PubMed: 33263328 Search on PubMedSearch on PubMed Central DOI: PubMed Abstract: The growth of diffraction-quality crystals and experimental phasing remain two of the main bottlenecks in protein crystallography