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68 In non-transformed cells, NRF2 promotes the entry of cysteine into the taurine synthesis pathway via CDO1, 69 and modestly limits the accumulation of cysteine and glutathione synthesis

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The extent to which this impacted lipogenic products (i.e., fatty acids and triglycerides) and whether this was connected to NRF2 activation was unclear

Protein arginine methyltransferase 4 (PRMT4), accelerates ferroptosis by inhibiting the NRF2/GPX4 pathway, thereby exacerbating DIC (85)