Glutathione is present in millimolar concentrations in most mammalian cells and it is involved in several fundamental biological functions, including free radical scavenging, detoxification of xenobiotics and carcinogens, redox reactions, biosynthesis of DNA, proteins and leukotrienes, as well as neurotransmission/neuromodulation
Furthermore, a recent study investigating patients with psoriatic arthritis (PsA) demonstrated that various biologic agents including infliximab, adalimumab, etanercept, golimumab, certolizumab, ustekinumab, and secukinumab were associated with an overall protective effect against liver fibrosis in individuals with MASLD
Chronic pain Another study from 1984, also published in European Neurology , examined DSIPs pain-reducing effects in seven patients with migraines, vasomotor headaches, tinnitus, and psychogenic pain attacks
All animal experiments performed in this study were approved by the relevant ethics committees, and all experimental procedures complied with local laws and ethical standards
R.RoychowdhuryS.et al (2020c)
