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It just wasnt the outcome people were hoping for. UPDATE: November 27 9:10AM ET

Large meals may also increase discomfort because GLP-1 medications slow digestion

This is underscored by the results of a clinical trial comparing the development of obese adults who received either semaglutide or liraglutide in addition to nutritional advice and physical activity, and significantly greater weight loss was achieved in the semaglutide group [102]