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Structural changes within the hoof and previous damage to the laminae can also leave affected horses more vulnerable to recurrence over time

The secondary evaluation outcomes were alterations in blood urea nitrogen (BUN), uric acid (UA), estimated glomerular filtration rate (eGFR), urinary AKI biomarkers, renal fibrosis biomarkers (transforming growth factor- 1 (TGF- 1 ), connective tissue growth factor (CTGF)), and traditional Chinese medicine (TCM) symptoms

Kleinrock says that while only a small subset of those drugs will complete Phase III trials, the diversity of approaches in drug types and the number of candidates in development are both reasons for optimism