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It does not aromatise and should therefore not present oestrogen-related side-effects

Endocrine and metabolic causes: Thyroid disease, uncontrolled diabetes, polycystic ovary syndrome (PCOS), and luteal phase defects affect hormone balance needed to sustain pregnancy

If appetite consistently rates below 3, you may be able to reduce your dose

It is worth noting that the compounds were tested in vitro using the Caco2 cell line and did not induce cell damage or death, which suggests a favorable preliminary safety profile and supports their potential for future drug development [62]