The most commonly reported side effects were mild and included headache, minor gastrointestinal disturbances (flatulence, mild diarrhea at high doses), upper respiratory symptoms, and mild injection site reactions
It upregulates growth hormone receptor expression and modulates the nitric oxide (NO) system, specifically counteracting both NO-synthase inhibition and excess NO-related damage in animal models 3
Improper dosing or unsupervised use may disrupt natural hormone balance or cause unwanted side effects
Because some peptides influence blood flow, angiogenesis (the growth of new blood vessels), or growth hormone signaling, they require caution in certain contexts
\n\n\n\n It is critical to note, however, that preclinical safety data no matter how consistently positive cannot be directly extrapolated to humans without proper clinical trials