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This is also when many people experience mild gastrointestinal side effects like loose stools or nauseasymptoms that typically resolve within 12 weeks as the body adapts to the dose

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Some individuals report early appetite changes with either medication, while others notice more gradual improvements

Anyone using an approved GLP-1 agent who experiences troublesome GI symptoms should speak to their prescribing clinician before making any changes to their regimen

These symptoms arise because semaglutide slows gastric emptying and alters intestinal motility and secretion, which can affect normal bowel patterns and fluid absorption