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Some sources report stability for up to 56 days, but 28 days is a safe guideline

In: Peterson ME, Talcott PA, eds

10.1016/j.cell.2015.11.055 82 Woo BaidalJ

Understanding these predispositions can provide context for medication selection and expected response patterns

Kidney Dysfunction: While the kidneys do not directly excrete vitamin B12 efficiently, impaired renal function may lead to elevated serum B12 levels by reducing the clearance of B12-binding proteins or altering their metabolism, thereby contributing to B12 accumulation 8

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