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Most people find that taking it at night does not interfere with their ability to fall asleep

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LIRA and SEMA gained approval from the Food and Drug Administration and the European Medicines Agency for weight loss in obese individuals or people who are overweight with BMI 27 kg/m 2 and have experienced at least one weight-associated comorbid condition (such as prediabetes, hypertension, dyslipidaemia, and OSA) combined with lifestyle modifications [63]

doi:10.1111/j.1440-1746.2010.06370.x Lee Y, Kim YK

Rarely, it can lead to severe complications such as pancreatitis or thyroid tumors