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The powder is reconstituted with the diluent before administration, yielding a yellow solution stabilized by excipients such as mannitol, polysorbate 80, sodium phosphate, and trehalose dihydrate

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Use a fresh needle every time, as reused needles develop microscopic burrs that tear tissue rather than puncturing cleanly

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However, insufficient evidence exists to justify the discontinuation of GLP-1 RAs before the procedure, and the ideal cessation timing for these agents remains indeterminate