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Since peptides' oral bioavailability is usually limited, they are often administered by injection into subcutaneous fat (as around the belly, thighs, or upper arms).24 TB4 or TB-500 injections are typically administered once per day, at any time of day, five days per week

More serious side effects that should prompt medical attention are increased blood pressure, heart palpitation, chest pain, shortness of breath, and swelling of the legs and ankles

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Both forms carry the same MHRA warning regarding the very rare risk of NAION (a serious eye condition)