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If nausea persists during dose increases, your healthcare provider might adjust your plan by extending the current dose for an additional 2-4 weeks, pausing further increases until symptoms improve, or temporarily lowering the dose
Methods Study protocol and subjects The protocol for this prospective study was approved by the Institutional Ethical Committee of Shinshu University School of Medicine, Matsumoto, Japan (document number: 2783) on July 8, 2014
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