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GLP-1 receptor agonist as an effective treatment for breast cancer-related lymphedema: a case report

In three different species (i.e., mice, rats, and musk shrews), we show that glucose-dependent insulinotropic polypeptide receptor (GIPR) signaling blocks emesis and attenuates illness behaviors elicited by GLP-1R activation, while maintaining reduced food intake, body weight loss, and improved glucose tolerance

10.1016/j.ajpath.2013.05.023 50 SuzukiK.KontaT.KudoK.SatoH.IkedaA.IchikawaK.et al (2013)

73,74,75 The expression of vascular endothelial growth factor (VEGF) and endothelin nitric oxide synthase (eNOS) are decreased in DE, which impairs cerebral artery endothelial function and results in decreased vascular autoregulatory response

La dose viene gradualmente aumentata per migliorare la tolleranza