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Studies have observed decreased cyclooxygenase-2 (COX-2) gene expression, reduced myeloperoxidase activity, and lower levels of pro-inflammatory cytokines including interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF-)

Comparative Proteomic Analysis of Saliva from Dogs with and without Obesity-Related Metabolic Dysfuntion

Neurochem Res 23:108591, PMID: 9704598 Gilbert KR, Aizenman E, Reynolds IJ (1991) Oxidized glutathione modulates N -methyl-d-aspartate- and depolarization-induced increases in intracellular Ca2+ in cultured rat forebrain neurons

The reduced refolding by the chaperone is possibly due to the inability of these Syn variants to adopt the native tertiary inert state, causing prolonged chaperone engagement

Excellent background on how glutathione supports cellular health (no treatment claims)