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Supportive in the treatment of chronic illness in general, IV glutathione is particularly effective in neurodegenerative conditions, cancer, liver disease, immunosuppressive states and persistent infections
However, a potential increase in the risk of AEs was also noted, including a higher incidence of overall AEs, discontinuation due to AEs, hypoglycemia, and gastrointestinal complications
10.2147/JIR.S329972 Summary Keywords PQQ, pyrroloquinoline quinone, fat, obesity, lipogenesis, mitochondria, inflammation, metabolic syndrome Citation Mohamad Ishak NS and Ikemoto K (2023) Pyrroloquinoline-quinone to reduce fat accumulation and ameliorate obesity progression
In this context, the antitumor activity reported for incretin-based polyagonists should not be interpreted as evidence for GCGR agonism alone, but rather as an indication that coordinated multi-receptor targeting may induce favorable systemic metabolic remodeling (62,63)