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GLP-1 (Glucagon-like Peptide-1) Receptor Agonist: Focuses on insulin secretion, glucose-dependent insulin sensitivity, and suppressing appetite via the brain's reward centers

Sasaoka T, Kobayashi M

For AOD-9604 and Tesamorelin: both have specific applications, but neither can match Retatrutide on overall fat loss evidence and magnitude of effect in a general population

That applies to both regular semaglutide and tirzepatide, as well as popular combination versions like semaglutide mixed with vitamin B12

Again, some level of consideration will have to be made for initial starting BMI, but just like the obese patients, a treat-to-target dose that considers weight + A1c goals should be the aim going forward