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Catalase in Endothelial Cell Defence (PubMed, 1987) GSH Redox Cycle as the Primary H2O2 Defence in Endothelial Cells A landmark mechanistic study published on PubMed examined the relative importance of the GSH redox cycle and catalase in protecting cultured endothelial cells against extracellular hydrogen peroxide flux a critical mediator of polymorphonuclear leukocyte-induced oxidant injury