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This helped a little with brightness, but the changes are slow and not very obvious yet

The only other human study, from 2015, was abandoned by 2016 the researchers had cancelled submission of the results [15]

Artificial intelligence (AI)-based algorithms, such as those validated in 2023, shows higher sensitivity for detecting NPDR due to more pronounced microvascular lesions (99, 100)

Regarding the refinement for Chc-Apl2.1 we have included secondary structure restraints, NCS torsion restrains, TLS refinement (at the beginning of the refinement one per chain and after the initial cycles the different TLS groups were calculated using phenix), grouped Bfactor refinement using PHENIX (1.21_5207) 58,59

With respect to the treatment of neurodegenerative diseases, the general pro-survival anti-apoptotic activity of HGF supports the use of HGF mimetics for treating neurodegenerative diseases including but not limited to Parkinson's disease, Huntington's disease, and amyotrophic lateral sclerosis (ALS), etc