The anti-stress activity of WS is most commonly attributed to its effects on the glucocorticoids cortisol and corticosterone (the major stress hormones in humans and rodents), respectively [166]
Kluck R, Muller S, Jagodzinski C, Hohenfellner K, Buscher A, Kemper MJ, Oh J, Billing H, Thumfart J, Weber LT, Acham-Roschitz B, Arbeiter K, Tonshoff B, Hagenberg M, Kanzelmeyer N, Pavicic L, Haffner D, Zivicnjak M (2022) Body growth, upper arm fat area, and clinical parameters in children with nephropathic cystinosis compared with other pediatric chronic kidney disease entities
The individual components of KLOW have been studied extensively in research settings with favorable safety profiles
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Although A-CDs and AA-CDs did not differ significantly in their ferrous ion-chelating ability, AA-CDs showed a higher clearance rate of intracellular ferrous ions in chondrocytes, which could be attributed to their superior chondrocyte internalization efficiency