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These chemicals then make it even harder to sleep well

doi: 10.3389/fnmol.2025.1549366 Received 21 December 2024 Accepted 12 March 2025 Published 07 April 2025 Volume 18 - 2025 Edited by Inigo Ruiz de Azua, Johannes Gutenberg University Mainz, Germany Reviewed by Beatrice Ferrari, San Matteo Hospital Foundation (IRCCS), Italy Ken-ichiro Nakajima, Nagoya University, Japan Keisuke Ito, University of Shizuoka, Japan Updates Copyright 2025 Shiimura, Kojima and Sato

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HFpEF is notoriously difficult to treat, and currently, only two drugs, the SGLT2 inhibitors dapagliflozin and empagliflozin, are FDA-approved to treat it

Brain Research Molecular Brain Research 30, 37-47CrossRefGoogle ScholarPubMed 48Kitamura, Y., Furukawa, M., Matsuoka, Y