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These changes contribute to a lower risk of cardiovascular disease and other chronic conditions related to obesity

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In addition, mouse studies have shown that butyrate contributes to maintain the colonic environment anaerobic through the activation of the peroxisome proliferator-activated receptor-gamma in colonocytes, which results in the induction of -oxidation (57)

GSH concentration is instead measured by either of two methods: by analysis of GS-NEM conjugates by HPLC in the same sample that is used to measure GSSG or, alternatively, by analysis of GSH by spectrophotometry (GSH recycling method) on one additional sample aliquot that has not been derivatized with NEM