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doi: 10.1073/pnas.0400181101

One of the most promising strategies to overcome this multi-drug resistance, MRP1-mediated CS, relies on the ability of certain ligands of MRP1 to induce a massive MRP1-dependent GSH efflux, that depletes the cells of their anti-oxidant defense, leading to their selective cell death 15

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Estimates suggest that the prevalence of DPN among adults with diabetes ranges from 6 to 51% [2, 3]

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