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When B12 May Be Especially Helpful for Sciatica B12 injections, or adding B12 to prolotherapy solution, may be particularly useful for individuals who experience: Burning or electric nerve pain Persistent tingling or numbness Slow recovery from nerve injury Chronic stress or fatigue alongside nerve pain Nutrient depletion from high training or work stress These signs often suggest that the nervous system may benefit from additional metabolic support

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But within reason