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Courcoulas, A.P., Christian, N.J., Belle, S.H., et al

With proper nutrition and training, muscle loss on semaglutide is comparable to, or better than, diet-only weight loss

However, other longitudinal observational studies in older adults have shown that higher amounts of MVPA are associated with a decreased likelihood of sarcopenia and/or its components (low appendicular lean mass and grip strength and slow TUG time), regardless of the amount of sedentary behavior [149,150]

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Knowledge of potential side effects like nausea, diarrhea, or vomiting is also recommended, although these effects generally diminish over time