They help curb appetite, slow gastric emptying, and reduce postprandial glucose spikes. Youve likely encountered names such as semaglutide (Ozempic, Wegovy, Rybelsus), tirzepatide (Mounjaro, Zepbound), dulaglutide (Trulicity), and liraglutide (Victoza, Saxenda). Early versions of these drugs required daily injection
The goal here is understanding the biology, not prescribing a regimen
Semaglutide is a GLP-1 receptor agonist - designed to act on GLP-1 receptors to support appetite regulation and slow gastric emptying
Consider Supplementation While dietary sources are important, supplementation can be beneficial, especially if dietary intake is insufficient
Clinical features We describe an unexpected case of regurgitation of a large volume of gastric contents upon induction of general anesthesia in a nondiabetic, nonobese patient despite a long preoperative fasting period (20 hr for solids and eight hours for clear fluids)